Studies on Penaeus orientolis KISHINOUYE-VIII

Studies on fluorinated pyrimidines. VIII. Further biochemical and metabolic investigations.

We have previously reported on the tumor inhibitory properties of 5-fluorouracil and 5-fluoroorotic acid (3, 4), prepared by Duschinsky et al. (5), and on the initial clinical trials of 5fluorouracil with patients with far advanced solid tumors (6). The metabolism of 5-fluorouracil and 5-fluororotic acid has been studied, data on excretion and tissue distribution in mice and man have been repor...

X-ray studies on phospholipid bilayers. VIII. Interactions with chlorpromazine.HCl.

Chlorpromazine is a widely used phenothiazine tranquilizer known to alter the shape of normal erythrocytes and their osmotic fragility. In order to understand the nature of the interactions chlorpromazine.HCl (CPZ.HCl) was made to interact with phospholipid bilayers formed by dimyristoylphosphatidylethanolamine (DMPE) and dimyristoylphosphatidylcholine (DMPC). This study was carried out by X-ra...

Studies on the Purification and Characterization of Human Factor VIII

The purified factor VIII has been found to be a macromolecular glycoprotein with a major subunit of 240,000, as shown by sodium dodecyl sulfate (SDS) polyacrylamide gel electrophoresis. Carbohydrate analysis of factor VIII gave values of 1% sialic acid, 2.8% hexosamine, and 1-2% hexose (mannose, galactose, and fucose). The lipid content was found to be less than 5% of the protein content, and i...

Short Communication: Chromosome studies on the marine shrimp Penaeus (Fenneropenaeus) merguiensis from the Persian Gulf

Short Communication: Chromosome studies on the marine shrimp Penaeus (Fenneropenaeus) merguiensis from the Persian Gulf